線粒體DNA A部分出版關于線粒體DNA的物理、化學和生化方面的高質量原稿，以及參與線粒體DNA代謝和/或相互作用的蛋白質。歡迎提交有關細胞漿和細胞外mtDNA、mtDNA完整性改變引起的功能障礙的手稿，以及詳細介紹在體內和體外操作mtDNA新方法的方法學論文。將考慮發表關于線粒體基因組DNA序列的描述性論文，以及使用線粒體DNA作為研究證據來源的人口遺傳學、系統遺傳學和人類進化領域的分析論文。該雜志還考慮了一些手稿，這些手稿檢驗了專門針對線粒體DNA序列使用的群體遺傳學和系統理論，以及討論線粒體DNA信息在醫學研究和人類進化生物學中的應用的論文。

Mitochondrial DNA Part A publishes original high-quality manuscripts on physical, chemical, and biochemical aspects of mtDNA and proteins involved in mtDNA metabolism, and/or interactions. Manuscripts on cytosolic and extracellular mtDNA, and on dysfunction caused by alterations in mtDNA integrity as well as methodological papers detailing novel approaches for mtDNA manipulation in vitro and in vivo are welcome. Descriptive papers on DNA sequences from mitochondrial genomes, and also analytical papers in the areas of population genetics, phylogenetics and human evolution that use mitochondrial DNA as a source of evidence for studies will be considered for publication. The Journal also considers manuscripts that examine population genetic and systematic theory that specifically address the use of mitochondrial DNA sequences, as well as papers that discuss the utility of mitochondrial DNA information in medical studies and in human evolutionary biology.