在過去的15年里，遺傳學和基因組學研究以令人困惑的速度發展。這些領域的技術正在應用于大量的生物學問題和實驗系統。公共科學圖書館遺傳學通過在生物學的各個領域發表杰出的原始貢獻，反映了這項研究的全面性和跨學科性質。公共科學圖書館遺傳學出版人類研究，以及對模型生物的研究——從老鼠和蒼蠅，到植物和細菌。我們的重點是研究廣泛的興趣，提供了重要的洞察生物過程或過程。主題包括(但不限于)基因發現和功能、群體遺傳學、基因組計劃、比較和功能基因組學、醫學遺傳學、疾病生物學、進化、基因表達、復雜性狀、染色體生物學和表觀遺傳學。

Genetics and genomics research has grown at a bewildering pace in the past 15 years. The techniques of these fields are being applied to a wealth of biological questions and experimental systems. PLOS Genetics reflects the full breadth and interdisciplinary nature of this research by publishing outstanding original contributions in all areas of biology.PLOS Genetics publishes human studies, as well as research on model organisms—from mice and flies, to plants and bacteria. Our emphasis is on studies of broad interest that provide significant insight into a biological process or processes. Topics include (but are not limited to) gene discovery and function, population genetics, genome projects, comparative and functional genomics, medical genetics, disease biology, evolution, gene expression, complex traits, chromosome biology, and epigenetics.